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ACL Findings2026

Position: Multimodal Large Language Models Can Significantly Advance Scientific Reasoning

Yibo Yan, Shen Wang, Jiahao Huo, Jingheng Ye, Zhendong Chu, Xuming Hu, Philip S. Yu, Carla P. Gomes, Bart Selman, Qingsong Wen

Abstract

Scientific reasoning, the process through which humans apply logic, evidence, and critical thinking to explore and interpret scientific phenomena, is essential in advancing knowledge reasoning across diverse fields. However, despite significant progress, current scientific reasoning models still struggle with generalization across domains and often fall short of multimodal perception. Multimodal Large Language Models (MLLMs), which integrate text, images, and other modalities, present an exciting opportunity to overcome these limitations and enhance scientific reasoning. Therefore, this position paper argues that MLLMs can significantly advance scientific reasoning across disciplines such as mathematics, physics, chemistry, and biology. First, we propose a four-stage research roadmap of scientific reasoning capabilities, and highlight the current state of MLLM applications in scientific reasoning, noting their ability to integrate and reason over diverse data types. Second, we summarize the key challenges that remain obstacles to achieving MLLM's full potential. To address these challenges, we propose actionable insights and suggestions for the future. Overall, our work offers a novel perspective on MLLM integration with scientific reasoning, providing the LLM community with a valuable vision for achieving Artificial General Intelligence (AGI).

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Cited by top-tier papers3

  1. How Do Multimodal Large Language Models Handle Complex Multimodal Reasoning? Placing Them in an Extensible Escape GameZiyue Wang, Yurui Dong, Fuwen Luo, Minyuan Ruan et al.ICCV 2025 · 9 citations
  2. CLEME2.0: Towards Interpretable Evaluation by Disentangling Edits for Grammatical Error CorrectionJingheng Ye, Zishan Xu, Yinghui Li, Linlin Song et al.ACL 2025
  3. LOTUS: Evolving Multimodal Unlearning via Hyperbolic Entailment and Lorentz TransportZekun Wang, Jingjie Zeng, Yingxu Li, Hongfei Lin et al.ACL 2026

Builds on64

  1. Measuring Massive Multitask Language UnderstandingDan Hendrycks, Collin Burns, Steven Basart, Andy Zou et al.ICLR 2021 · 7,905 citations
  2. Solving Quantitative Reasoning Problems with Language ModelsAitor Lewkowycz, Anders Andreassen, David Dohan, Ethan Dyer et al.NeurIPS 2022 · 2,039 citations
  3. Large Language Models Can Be Easily Distracted by Irrelevant ContextFreda Shi, Xinyun Chen, Kanishka Misra, Nathan Scales et al.ICML 2023 · 970 citations
  4. MetaMath: Bootstrap Your Own Mathematical Questions for Large Language ModelsLonghui Yu, Weisen Jiang, Han Shi, Jincheng Yu et al.ICLR 2024 · 637 citations
  5. MAmmoTH: Building Math Generalist Models through Hybrid Instruction TuningXiang Yue, Xingwei Qu, Ge Zhang, Yao Fu et al.ICLR 2024 · 558 citations

Related papers

  1. MME-SCI: A Comprehensive and Challenging Science Benchmark for Multimodal Large Language ModelsJiacheng Ruan, Dan Jiang, Xian Gao, Ting Liu et al.AAAI 2026 · 3 citations
  2. SciVQR: A Multidisciplinary Multimodal Benchmark for Advanced Scientific Reasoning EvaluationLongteng Guo, Xuanxu Lin, Dongze Hao, Tongtian Yue et al.ACL Findings 2026
  3. MMSciBench: Benchmarking Language Models on Chinese Multimodal Scientific ProblemsXinwu Ye, Chengfan Li, Siming Chen, Wei Wei et al.ACL Findings 2025 · 1 citation
  4. MMReason: An Open-Ended Multi-Modal Multi-Step Reasoning Benchmark for MLLMs Toward AGIHuanjin Yao, Jiaxing Huang, Yawen Qiu, Michael K. Chen et al.ICCV 2025 · 4 citations
  5. A Survey of Mathematical Reasoning in the Era of Multimodal Large Language Model: Benchmark, Method & ChallengesYibo Yan, Jiamin Su, Jianxiang He, Fangteng Fu et al.ACL Findings 2025 · 13 citations
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