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ReasonMed: A 370K Multi-Agent Generated Dataset for Advancing Medical Reasoning

Yu Sun, Xingyu Qian, Weiwen Xu, Hao Zhang, Chenghao Xiao, Long Li, Deli Zhao, Wenbing Huang, Tingyang Xu, Qifeng Bai, Yu Rong

2025Year
1Citations
6Top-tier citations

Abstract

Reasoning-based large language models have excelled in mathematics and programming, yet their potential in knowledge-intensive medical question answering remains underexplored and insufficiently validated in clinical contexts. To bridge this gap, we introduce ReasonMed, the largest medical reasoning dataset to date, comprising 370k high-quality examples distilled from 1.75 million initial reasoning paths generated by complementary LLMs and curated through a cost-efficient easy-medium-difficult (EMD) pipeline. ReasonMed is built through a multi-agent generation, verification, and refinement process, in which an Error Refiner improves reasoning paths by correcting errorprone steps identified by a verifier. Using Rea-sonMed, we investigate effective strategies for training medical reasoning models and find that integrating detailed CoT reasoning with concise answer summaries yields the most robust fine-tuning results. Models trained on Rea-sonMed set a new benchmark: ReasonMed-7B surpasses the prior best sub-10B models by 4.17% and even exceeds LLaMA3.1-70B on PubMedQA by 4.60%. When scaled to ReasonMed-14B, it remains highly competitive, underscoring consistent scaling potential. 1

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