HI-DR: Exploiting Health Status-Aware Attention and an EHR Graph+ for Effective Medication Recommendation
Taeri Kim, Jiho Heo, Hyunjoon Kim, Sang-Wook Kim
Abstract
We focus on the medication recommendation problem aiming to recommend accurate medications for a patient's current visit. Most existing methods for this problem utilize the patient's current health status, medications prescribed at her past visits, and an Electronic Health Records (EHR) graph which represents whether medications have been coprescribed. However, we point out their two key limitations:
(1) they have difficulty in utilizing only the medications which have been prescribed in health status similar to the patient's current health status, regardless of whether they are prescribed at her past visits or at other patients' visits; (2) for two medications that have ever been co-prescribed, their EHR graph does not consider the degree to which one medication is prescribed together when the other is prescribed. To address these two limitations, we propose a novel medication recommendation framework, named HI-DR (pronounced as 'Hi Doctor'), composed of following two core ideas: (Idea 1) Health status-aware attentIon; (Idea 2) an electronic health recorDs gRaph+. Extensive experiments on realworld datasets demonstrate the significant superiority of HI-DR (up to 18.69% higher accuracy than the best competitor) and the effectiveness of two core ideas in HI-DR.
Ask about this paper
Your agent reads all of it.
Lune indexed this paper to the last equation, along with the top-tier papers that cite it. Ask a question and the answer quotes them.
Your agent calls
Luneget_paper_fulltext
Free to start. No credit card required.
Terminal
Install the CLIlune papers fulltext 250188eb-79c1-486e-978b-d1db0c3d989eCited by top-tier papers2
- Knowledge-Enhanced Explainable Hypergraph Convolution Network for Medication RecommendationZihan Zhang, Hongzhi Liu, Xiaoshuang Guo, Tianqi Sun et al.AAAI 2026
- Awaken the Giant: Activating LLMs via Deep Model Guidance for Boundary-aware Medication RecommendationHang Lv, Zixuan Guo, Yanchao Tan, Wanzi Shao et al.KDD 2026
Builds on6
- Conditional Generation Net for Medication RecommendationRui Wu, Zhaopeng Qiu, Jiacheng Jiang, Guilin Qi et al.WWW 2022 · 135 citations
- Digraph Inception Convolutional NetworksZekun Tong, Yuxuan Liang, Changsheng Sun, Xinke Li et al.NeurIPS 2020 · 132 citations
- Drug Package Recommendation via Interaction-aware Graph InductionZhi Zheng, Chao Wang, Tong Xu, Dazhong Shen et al.WWW 2021 · 78 citations
- Debiased, Longitudinal and Coordinated Drug Recommendation through Multi-Visit Clinic RecordsHongda Sun, Shufang Xie, Shuqi Li, Yuhan Chen et al.NeurIPS 2022 · 57 citations
- REFINE: A Fine-Grained Medication Recommendation System Using Deep Learning and Personalized Drug Interaction ModelingSuman Bhoi, Mong-Li Lee, Wynne Hsu, Ngiap Chuan TanNeurIPS 2023 · 43 citations
Related papers
- VITA: 'Carefully Chosen and Weighted Less' Is Better in Medication RecommendationTaeri Kim, Jiho Heo, Hongil Kim, Kijung Shin et al.AAAI 2024 · 32 citations
- MedAlign: Enhancing Combinatorial Medication Recommendation with Multi-modality AlignmentHang Lv, Zixuan Guo, Zijie Wu, Yanchao Tan et al.ACM MM 2025 · 4 citations
- Context-Aware Safe Medication Recommendations with Molecular Graph and DDI Graph EmbeddingQianyu Chen, Xin Li, Kunnan Geng, Mingzhong WangAAAI 2023 · 38 citations
- DMRNet: Effective Network for Accurate Discharge Medication RecommendationJiyun Shi, Yuqiao Wang, Chi Zhang, Zhaojing Luo et al.ICDE 2024 · 7 citations
- Context-Aware Health Event Prediction via Transition Functions on Dynamic Disease GraphsChang Lu, Tian Han, Yue NingAAAI 2022 · 67 citations
