BioFEG: Generate Latent Features for Biomedical Entity Linking

Biomedical entity linking is an essential task in biomedical text processing, which aims to map entity mentions in biomedical text, such as clinical notes, to standard terms in a given knowledge base. However, this task is challenging due to the rarity of many biomedical entities in real-world scenarios, which often leads to a lack of annotated data for them. Limited by understanding these unseen entities, traditional biomedical entity linking models suffer from multiple types of linking errors. In this paper, we propose a novel latent feature generation framework BioFEG to address these challenges. Specifically, our BioFEG leverages domain knowledge to train a generative adversarial network, which generates latent semantic features of corresponding mentions for unseen entities. Utilizing these features, we fine-tune our entity encoder to capture fine-grained coherence information of unseen entities and better understand them. This allows models to make linking decisions more accurately, particularly for ambiguous mentions involving rare entities. Extensive experiments on the two benchmark datasets demonstrate the superiority of our proposed framework.