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NeurIPS2025顶会

Panacea: Mitigating Harmful Fine-tuning for Large Language Models via Post-fine-tuning Perturbation

Yibo Wang, Tiansheng Huang, Li Shen, Huanjin Yao, Haotian Luo, Rui Liu, Naiqiang Tan, Jiaxing Huang, Dacheng Tao

2025年份
22被引次数
11顶会引用

摘要

Harmful fine-tuning attack introduces significant security risks to the fine-tuning services. Main-stream defenses aim to vaccinate the model such that the later harmful fine-tuning attack is less effective. However, our evaluation results show that such defenses are fragile-with a few fine-tuning steps, the model still can learn the harmful knowledge. To this end, we do further experiment and find that an embarrassingly simple solution-adding purely random perturbations to the fine-tuned model, can recover the model from harmful behaviors, though it leads to a degradation in the model's fine-tuning performance. To address the degradation of fine-tuning performance, we further propose Panacea, which optimizes an adaptive perturbation that will be applied to the model after fine-tuning. Panacea maintains model's safety alignment performance without compromising downstream fine-tuning performance. Comprehensive experiments are conducted on different harmful ratios, fine-tuning tasks and mainstream LLMs, where the average harmful scores are reduced by up-to 21.2%, while maintaining fine-tuning performance. As a by-product, we analyze the adaptive perturbation and show that different layers in various LLMs have distinct safety affinity, which coincide with finding from several previous study. Source code available at https://github. com/w-yibo/Panacea . Vaccine [8] and RepNoise [9] are two representative defenses against the harmful fine-tuning attack.

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