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ICML2026Top-tier venue

CauSciBench: Can LLMs Automate Causal Inference in Real-World Scientific Research?

Sawal Acharya, Terry J Zhang, Andrew Kim, Rahul B Shrestha, Xianlin Sun, Pepijn Cobben, Maximilian Mordig, Jacob Emmerson, Anahita Haghighat, Furkan Danisman, Yuen Chen, Clijo Jose

2026Year

Abstract

Identifying and estimating causal relationships from data is a crucial component of empirical research. While large language model-powered tools have shown potential for assisting research workflows, their ability to perform end-to-end causal inference remains underexplored. We introduce CauSciBench, a benchmark that puts LLM-powered tools to the test on causality- driven research questions. Unlike previous related benchmarks that focus on coding alone, CauSciBench enables evaluation across the full pipeline of causal inference: from method and variable selection to computation of causal effects and statistical interpretation in the context of real-world research problems. We evaluated 7 frontier models on over 300 queries derived from scientific publications, textbook problems, sem- inal datasets, and synthetic scenarios. Results show that models consistently perform worse on real datasets, with the key bottleneck being the selection of an appropriate causal inference method.

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