Towards Unifying Medical Vision-and-Language Pre-training via Soft Prompts
Zhihong Chen, Shizhe Diao, Benyou Wang, Guanbin Li, Xiang Wan
Abstract
Medical vision-and-language pre-training (Med-VLP) has shown promising improvements on many downstream medical tasks owing to its applicability to extracting generic representations from medical images and texts. Practically, there exist two typical types, i.e., the fusion-encoder type and the dual-encoder type, depending on whether a heavy fusion module is used. The former is superior at multi-modal tasks owing to the sufficient interaction between modalities; the latter is good at uni-modal and cross-modal tasks due to the single-modality encoding ability. To take advantage of these two types, we propose an effective yet straightforward scheme named PTUnifier to unify the two types. We first unify the input format by introducing visual and textual prompts, which serve as DETR-like queries that assist in extracting features when one of the modalities is missing. By doing so, a single model could serve as a foundation model that processes various tasks adopting different input formats (i.e., image-only, text-only, and image-text-pair). Furthermore, we construct a prompt pool (instead of static ones) to improve diversity and scalability, enabling queries conditioned on different input instances. Experimental results show that our approach achieves competitive results on a broad range of tasks, spanning uni-modal tasks (i.e., image/text classification and text summarization), cross-modal tasks (i.e., image-to-text generation and image-text/text-image retrieval), and multi-modal tasks (i.e., visual question answering), demonstrating the effectiveness of our approach. Note that the adoption of prompts is orthogonal to most existing Med-VLP approaches and could be a beneficial and complementary extension to these approaches.1
Ask about this paper
Your agent reads all of it.
Lune indexed this paper to the last equation, along with the top-tier papers that cite it. Ask a question and the answer quotes them.
Your agent calls
Luneget_paper_fulltext
Free to start. No credit card required.
Terminal
Install the CLIlune papers fulltext ed7b0232-b9e3-497f-be85-cecf20e88a5bCited by top-tier papers10
- C-TPT: Calibrated Test-Time Prompt Tuning for Vision-Language Models via Text Feature DispersionHee Suk Yoon, Eunseop Yoon, Joshua Tian Jin Tee, Mark A. Hasegawa-Johnson et al.ICLR 2024 · 84 citations
- GEMeX: A Large-Scale, Groundable, and Explainable Medical VQA Benchmark for Chest X-Ray DiagnosisBo Liu, Ke Zou, Li-Ming Zhan, Zexin Lu et al.ICCV 2025 · 10 citations
- A-TPT: Angular Diversity Calibration Properties for Test-Time Prompt Tuning of Vision-Language ModelsShihab Aaqil Ahamed, Udaya Sampath K. Perera Miriya Thanthrige, Ranga Rodrigo, Muhammad Haris KhanICLR 2026 · 5 citations
- Detecting Any instruction-to-answer interaction relationship: Universal Instruction-to-Answer Navigator for Med-VQAZhongze Wu, Hongyan Xu, Yitian Long, Shan You et al.ICML 2024 · 4 citations
- Large-scale and Fine-grained Vision-language Pre-training for Enhanced CT Image UnderstandingZhongyi Shui, Jianpeng Zhang, Weiwei Cao, Sinuo Wang et al.ICLR 2025
Builds on22
- Learning Transferable Visual Models From Natural Language SupervisionAlec Radford, Jong Wook Kim, Chris Hallacy, Aditya Ramesh et al.ICML 2021 · 47,906 citations
- A Simple Framework for Contrastive Learning of Visual RepresentationsTing Chen, Simon Kornblith, Mohammad Norouzi, Geoffrey E. HintonICML 2020 · 24,064 citations
- An Image is Worth 16x16 Words: Transformers for Image Recognition at ScaleAlexey Dosovitskiy, Lucas Beyer, Alexander Kolesnikov, Dirk Weissenborn et al.ICLR 2021 · 21,477 citations
- Scaling Up Visual and Vision-Language Representation Learning With Noisy Text SupervisionChao Jia, Yinfei Yang, Ye Xia, Yi-Ting Chen et al.ICML 2021 · 5,401 citations
- Align before Fuse: Vision and Language Representation Learning with Momentum DistillationJunnan Li, Ramprasaath R. Selvaraju, Akhilesh Gotmare, Shafiq R. Joty et al.NeurIPS 2021 · 2,985 citations
Related papers
- MedUnifier: Unifying Vision-and-Language Pre-training on Medical Data with Vision Generation Task using Discrete Visual RepresentationsZiyang Zhang, Yang Yu, Yucheng Chen, Xulei Yang et al.CVPR 2025
- Align, Reason and Learn: Enhancing Medical Vision-and-Language Pre-training with KnowledgeZhihong Chen, Guanbin Li, Xiang WanACM MM 2022 · 82 citations
- Med-UniC: Unifying Cross-Lingual Medical Vision-Language Pre-Training by Diminishing BiasZhongwei Wan, Che Liu, Mi Zhang, Jie Fu et al.NeurIPS 2023 · 114 citations
- E2E-VLP: End-to-End Vision-Language Pre-training Enhanced by Visual LearningHaiyang Xu, Ming Yan, Chenliang Li, Bin Bi et al.ACL 2021
- Unified Vision-Language Pre-Training for Image Captioning and VQALuowei Zhou, Hamid Palangi, Lei Zhang, Houdong Hu et al.AAAI 2020 · 1,047 citations
