MEDFAIR: Benchmarking Fairness for Medical Imaging
Yongshuo Zong, Yongxin Yang, Timothy M. Hospedales
Abstract
A multitude of work has shown that machine learning-based medical diagnosis systems can be biased against certain subgroups of people. This has motivated a growing number of bias mitigation algorithms that aim to address fairness issues in machine learning. However, it is difficult to compare their effectiveness in medical imaging for two reasons. First, there is little consensus on the criteria to assess fairness. Second, existing bias mitigation algorithms are developed under different settings, e.g., datasets, model selection strategies, backbones, and fairness metrics, making a direct comparison and evaluation based on existing results impossible. In this work, we introduce MEDFAIR, a framework to benchmark the fairness of machine learning models for medical imaging. MEDFAIR covers eleven algorithms from various categories, nine datasets from different imaging modalities, and three model selection criteria. Through extensive experiments, we find that the under-studied issue of model selection criterion can have a significant impact on fairness outcomes; while in contrast, state-of-the-art bias mitigation algorithms do not significantly improve fairness outcomes over empirical risk minimization (ERM) in both in-distribution and out-of-distribution settings. We evaluate fairness from various perspectives and make recommendations for different medical application scenarios that require different ethical principles. Our framework provides a reproducible and easy-to-use entry point for the development and evaluation of future bias mitigation algorithms in deep learning. Code is available at https://github.com/ys-zong/MEDFAIR.
Ask about this paper
Your agent reads all of it.
Lune indexed this paper to the last equation, along with the top-tier papers that cite it. Ask a question and the answer quotes them.
Your agent calls
Luneget_paper_fulltext
Free to start. No credit card required.
Terminal
Install the CLIlune papers fulltext ed0da620-e665-4e3c-a2cd-dc6622b44a28Cited by top-tier papers8
- FairTune: Optimizing Parameter Efficient Fine Tuning for Fairness in Medical Image AnalysisRaman Dutt, Ondrej Bohdal, Sotirios A. Tsaftaris, Timothy M. HospedalesICLR 2024 · 30 citations
- OxonFair: A Flexible Toolkit for Algorithmic FairnessEoin Delaney, Zihao Fu, Sandra Wachter, Brent D. Mittelstadt et al.NeurIPS 2024 · 13 citations
- Benchmarking Bias Mitigation Toward Fairness Without Harm from Vision to LVLMsXuwei Tan, Ziyu Hu, Xueru ZhangICLR 2026 · 4 citations
- Toward Fair and Accurate Cross-Domain Medical Image Segmentation: a Vlm-Driven Active Domain Adaptation ParadigmHongqiu Wang, Wu Chen, Xiangde Luo, Zhaohu Xing et al.ICCV 2025 · 3 citations
- Subgroups Matter for Robust Bias MitigationAnissa Alloula, Charles Jones, Ben Glocker, Bartlomiej W. PapiezICML 2025
Builds on12
- Sharpness-aware Minimization for Efficiently Improving GeneralizationPierre Foret, Ariel Kleiner, Hossein Mobahi, Behnam NeyshaburICLR 2021 · 1,861 citations
- SWAD: Domain Generalization by Seeking Flat MinimaJunbum Cha, Sanghyuk Chun, Kyungjae Lee, Han-Cheol Cho et al.NeurIPS 2021 · 630 citations
- Fairness without Demographics through Adversarially Reweighted LearningPreethi Lahoti, Alex Beutel, Jilin Chen, Kang Lee et al.NeurIPS 2020 · 406 citations
- Minimax Pareto Fairness: A Multi Objective PerspectiveNatalia Martínez, Martín Bertrán, Guillermo SapiroICML 2020 · 232 citations
- Learning Debiased Representation via Disentangled Feature AugmentationJungsoo Lee, Eungyeup Kim, Juyoung Lee, Jihyeon Lee et al.NeurIPS 2021 · 203 citations
Related papers
- The Boundaries of Fair AI in Medical Image Prognosis: A Causal PerspectiveThai-Hoang Pham, Jiayuan Chen, Seungyeon Lee, Yuanlong Wang et al.NeurIPS 2025 · 3 citations
- A Large-Scale Empirical Study on Improving the Fairness of Image Classification ModelsJunjie Yang, Jiajun Jiang, Zeyu Sun, Junjie ChenISSTA 2024 · 4 citations
- Fairea: a model behaviour mutation approach to benchmarking bias mitigation methodsMax Hort, Jie M. Zhang, Federica Sarro, Mark HarmanFSE 2021 · 75 citations
- Rethinking Fair Representation Learning for Performance-Sensitive TasksCharles Jones, Fabio De Sousa Ribeiro, Mélanie Roschewitz, Daniel C. Castro et al.ICLR 2025
- Do the machine learning models on a crowd sourced platform exhibit bias? an empirical study on model fairnessSumon Biswas, Hridesh RajanFSE 2020 · 96 citations
