Motif Simplification for BioFabric Network Visualizations: Improving Pattern Recognition and Interpretation

Detecting and interpreting common patterns in relational data is crucial for understanding complex topological structures across various domains. These patterns, or network motifs, can often be detected algorithmically. However, visual inspection remains vital for exploring and discovering patterns. This paper focuses on presenting motifs within BioFabric network visualizations-a unique technique that opens opportunities for research on scaling to larger networks, design variations, and layout algorithms to better expose motifs. Our goal is to show how highlighting motifs can assist users in identifying and interpreting patterns in BioFabric visualizations. To this end, we leverage existing motif simplification techniques. We replace edges with glyphs representing fundamental motifs such as staircases, cliques, paths, and connector nodes. The results of our controlled experiment and usage scenarios demonstrate that motif simplification for BioFabric is useful for detecting and interpreting network patterns. Our participants were faster and more confident using the simplified view without sacrificing accuracy. The efficacy of our current motif simplification approach depends on which extant layout algorithm is used. We hope our promising findings on user performance will motivate future research on layout algorithms tailored to maximizing motif presentation. Our supplemental material is available at https://osf.io/f8s3g/?view_only=7e2df9109dfd4e6c85b89ed828320843.