Estimating the Effects of Continuous-valued Interventions using Generative Adversarial Networks
Ioana Bica, James Jordon, Mihaela van der Schaar
Abstract
While much attention has been given to the problem of estimating the effect of discrete interventions from observational data, relatively little work has been done in the setting of continuous-valued interventions, such as treatments associated with a dosage parameter. In this paper, we tackle this problem by building on a modification of the generative adversarial networks (GANs) framework. Our model, SCIGAN, is flexible and capable of simultaneously estimating counterfactual outcomes for several different continuous interventions. The key idea is to use a significantly modified GAN model to learn to generate counterfactual outcomes, which can then be used to learn an inference model, using standard supervised methods, capable of estimating these counterfactuals for a new sample. To address the challenges presented by shifting to continuous interventions, we propose a novel architecture for our discriminator -we build a hierarchical discriminator that leverages the structure of the continuous intervention setting. Moreover, we provide theoretical results to support our use of the GAN framework and of the hierarchical discriminator. In the experiments section, we introduce a new semi-synthetic data simulation for use in the continuous intervention setting and demonstrate improvements over the existing benchmark models. * Equal contribution. 2 For ease of exposition, we will sometimes refer to interventions as treatments and to the associated continuous parameter as the dosage throughout the paper. 34th Conference on Neural Information Processing Systems (NeurIPS 2020),
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Install the CLIlune papers fulltext b22f51e6-eab1-4127-9bff-fbbb0c6adb10Cited by top-tier papers38
- Time Series Deconfounder: Estimating Treatment Effects over Time in the Presence of Hidden ConfoundersIoana Bica, Ahmed M. Alaa, Mihaela van der SchaarICML 2020 · 133 citations
- VCNet and Functional Targeted Regularization For Learning Causal Effects of Continuous TreatmentsLizhen Nie, Mao Ye, Qiang Liu, Dan NicolaeICLR 2021 · 81 citations
- Causal Effect Inference for Structured TreatmentsJean Kaddour, Yuchen Zhu, Qi Liu, Matt J. Kusner et al.NeurIPS 2021 · 62 citations
- OrganITE: Optimal transplant donor organ offering using an individual treatment effectJeroen Berrevoets, James Jordon, Ioana Bica, Alexander Gimson et al.NeurIPS 2020 · 51 citations
- Generalization Bounds for Estimating Causal Effects of Continuous TreatmentsXin Wang, Shengfei Lyu, Xingyu Wu, Tianhao Wu et al.NeurIPS 2022 · 38 citations
Builds on3
- Estimating counterfactual treatment outcomes over time through adversarially balanced representationsIoana Bica, Ahmed M. Alaa, James Jordon, Mihaela van der SchaarICLR 2020 · 224 citations
- Learning Counterfactual Representations for Estimating Individual Dose-Response CurvesPatrick Schwab, Lorenz Linhardt, Stefan Bauer, Joachim M. Buhmann et al.AAAI 2020 · 159 citations
- Time Series Deconfounder: Estimating Treatment Effects over Time in the Presence of Hidden ConfoundersIoana Bica, Ahmed M. Alaa, Mihaela van der SchaarICML 2020 · 133 citations
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