Small Agent Group is the Future of Digital Health
Yuqiao Meng, Luoxi Tang, Dazheng Zhang, Rafael Brens, Elvys Romero, Nancy Guo, Safa Elkefi, Zhaohan Xi
Abstract
The rapid adoption of large language models (LLMs) in digital health has been driven by a "scaling-first" philosophy, i.e., the assumption that clinical intelligence increases with model size and data. However, real-world clinical needs include not only effectiveness, but also reliability and reasonable deployment cost. Since clinical decision-making is inherently collaborative, we challenge the monolithic scaling paradigm and ask whether a Small Agent Group (SAG) can support better clinical reasoning. SAG shifts from single-model intelligence to collective expertise by distributing reasoning, evidence-based analysis, and critical audit through a collaborative deliberation process. To assess the clinical utility of SAG, we conduct extensive evaluations using diverse clinical metrics spanning effectiveness, reliability, and deployment cost. Our results show that SAG achieves superior performance compared to a single giant model, both with and without additional optimization or retrieval-augmented generation. These findings suggest that the synergistic reasoning represented by SAG can substitute for model parameter growth in clinical settings. Overall, SAG offers a scalable solution to digital health that better balances effectiveness, reliability, and deployment efficiency.
Ask about this paper
Your agent reads all of it.
Lune indexed this paper to the last equation, along with the top-tier papers that cite it. Ask a question and the answer quotes them.
Your agent calls
Luneget_paper_fulltext
Free to start. No credit card required.
Terminal
Install the CLIlune papers fulltext a9d5e350-1e0e-4646-9a77-6616fd72a684Builds on9
- Retrieval Augmented Language Model Pre-TrainingKelvin Guu, Kenton Lee, Zora Tung, Panupong Pasupat et al.ICML 2020 · 2,937 citations
- CAMEL: Communicative Agents for "Mind" Exploration of Large Language Model SocietyGuohao Li, Hasan Hammoud, Hani Itani, Dmitrii Khizbullin et al.NeurIPS 2023 · 1,975 citations
- Improving Factuality and Reasoning in Language Models through Multiagent DebateYilun Du, Shuang Li, Antonio Torralba, Joshua B. Tenenbaum et al.ICML 2024 · 1,562 citations
- Self-Consistency Improves Chain of Thought Reasoning in Language ModelsXuezhi Wang, Jason Wei, Dale Schuurmans, Quoc V. Le et al.ICLR 2023 · 681 citations
- Encouraging Divergent Thinking in Large Language Models through Multi-Agent DebateTian Liang, Zhiwei He, Wenxiang Jiao, Xing Wang et al.EMNLP 2024 · 177 citations
Related papers
- Why Specialist Models Still Matter: A Heterogeneous Multi-Agent Paradigm for Medical Artificial IntelligenceYanan Wang, Shuaicong Hu, Jian Liu, Guohui Zhou et al.ICML 2026
- ColaCare: Enhancing Electronic Health Record Modeling through Large Language Model-Driven Multi-Agent CollaborationZixiang Wang, Yinghao Zhu, Huiya Zhao, Xiaochen Zheng et al.WWW 2025 · 34 citations
- Social Dynamics as Critical Vulnerabilities that Undermine Objective Decision-Making in LLM CollectivesChanggeon Ko, Jisu Shin, Hoyun Song, Huije Lee et al.ACL 2026 · 1 citation
- MedLA: A Logic-Driven Multi-Agent Framework for Complex Medical Reasoning with Large Language ModelsSiqi Ma, Jiajie Huang, Fan Zhang, Jinlin Wu et al.AAAI 2026 · 10 citations
- MDAgents: An Adaptive Collaboration of LLMs for Medical Decision-MakingYubin Kim, Chanwoo Park, Hyewon Jeong, Yik Siu Chan et al.NeurIPS 2024 · 291 citations
