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When Correct Beliefs Collapse: Epistemic Resilience of LLMs under Clinical Pressure

Boyu Xiao, Xiuqi Tian, Xuwen Song, Haochun Wang, Guanchun Song, Sendong Zhao, Bing Qin

2026Year

Abstract

Despite strong medical benchmark accuracy, LLMs can exhibit severe multi-turn sycophancy in clinical dialogue, abandoning initial correct diagnosis under escalating pressure. We propose Med-Stress, a targeted stress test framework that evaluates belief stability under escalating pressure. Across nine frontier large language models (LLMs), we find a clear dissociation between medical knowledge and robustness: high initial diagnostic capability does not imply high belief stability, yielding large knowledge-robustness gaps for several LLMs. To mitigate this failure mode, we propose a lightweight inference-time defense, RBED (Role-Based Epistemic Defense), and R-FT (Resilience-oriented Fine-Tuning), a training-time approach that internalizes evidence-based resistance to pressure. Experiments show that R-FT nearly eliminates belief change and substantially improves robustness.

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