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ACL Findings2025

A Survey of Large Language Models in Psychotherapy: Current Landscape and Future Directions

Hongbin Na, Yining Hua, Zimu Wang, Tao Shen, Beibei Yu, Lilin Wang, Wei Wang, John B. Torous, Ling Chen

Abstract

Mental health is increasingly critical in contemporary healthcare, with psychotherapy demanding dynamic, context-sensitive interactions that traditional NLP methods struggle to capture. Large Language Models (LLMs) offer significant potential for addressing this gap due to their ability to handle extensive context and multi-turn reasoning. This review introduces a conceptual taxonomy dividing psychotherapy into interconnected stages-assessment, diagnosis, and treatment-to systematically examine LLM advancements and challenges. Our comprehensive analysis reveals imbalances in current research, such as a focus on common disorders, linguistic biases, fragmented methods, and limited theoretical integration. We identify critical challenges including capturing dynamic symptom fluctuations, overcoming linguistic and cultural biases, and ensuring diagnostic reliability. Highlighting future directions, we advocate for continuous multi-stage modeling, real-time adaptive systems grounded in psychological theory, and diversified research covering broader mental disorders and therapeutic approaches, aiming toward more holistic and clinically integrated psychotherapy LLMs systems.

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Cited by top-tier papers3

  1. Script-Strategy Aligned Generation: Aligning LLMs with Expert-Crafted Dialogue Scripts and Therapeutic Strategies for PsychotherapyXin Sun, Jan de Wit, Zhuying Li, Jiahuan Pei et al.CSCW 2025 · 6 citations
  2. Cognitive Policy-Driven LLM for Diagnosis and Intervention of Cognitive Distortions in Emotional Support ConversationLin Zhong, Renjin Zhu, Shujuan Ma, Jinhao Cui et al.ACL 2026
  3. Responsible Evaluation of AI for Mental HealthHiba Arnaout, Anmol Goel, H. Andrew Schwartz, Steffen Eberhardt et al.ACL 2026

Builds on28

  1. Mental-LLM: Leveraging Large Language Models for Mental Health Prediction via Online Text DataXuhai Xu, Bingsheng Yao, Yuanzhe Dong, Saadia Gabriel et al.UbiComp 2024 · 281 citations
  2. Towards Interpretable Mental Health Analysis with Large Language ModelsKailai Yang, Shaoxiong Ji, Tianlin Zhang, Qianqian Xie et al.EMNLP 2023 · 114 citations
  3. MindfulDiary: Harnessing Large Language Model to Support Psychiatric Patients' JournalingTaewan Kim, Seolyeong Bae, Hyun Ah Kim, Su-Woo Lee et al.CHI 2024 · 112 citations
  4. Facilitating Self-Guided Mental Health Interventions Through Human-Language Model Interaction: A Case Study of Cognitive RestructuringAshish Sharma, Kevin Rushton, Inna Wanyin Lin, Theresa Nguyen et al.CHI 2024 · 104 citations
  5. SoulChat: Improving LLMs' Empathy, Listening, and Comfort Abilities through Fine-tuning with Multi-turn Empathy ConversationsYirong Chen, Xiaofen Xing, Jingkai Lin, Huimin Zheng et al.EMNLP Findings 2023 · 81 citations

Related papers

  1. A Conditional Companion: Lived Experiences of People with Mental Health Disorders Using LLMs: Conditional Companion: LLMs & Mental HealthAditya Kumar Purohit, Hendrik HeuerCHI 2026 · 3 citations
  2. From Conversation to Automation: Leveraging LLMs for Problem-Solving Therapy AnalysisElham Aghakhani, Lu Wang, Karla T. Washington, George Demiris et al.ACL Findings 2025 · 5 citations
  3. How to Enable Effective Cooperation Between Humans and NLP Models: A Survey of Principles, Formalizations, and BeyondChen Huang, Yang Deng, Wenqiang Lei, Jiancheng Lv et al.ACL 2025
  4. Empowering Psychotherapy with Large Language Models: Cognitive Distortion Detection through Diagnosis of Thought PromptingZhiyu Chen, Yujie Lu, William Yang WangEMNLP Findings 2023 · 22 citations
  5. MentalSeek-Dx: Towards Progressive Hypothetico-Deductive Reasoning for Real-world Psychiatric DiagnosisXiao Sun, Yuming Yang, Xinyi Jiang, Yu Tian et al.ACL 2026 · 1 citation
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