Hierarchical Pretraining on Multimodal Electronic Health Records
Xiaochen Wang, Junyu Luo, Jiaqi Wang, Ziyi Yin, Suhan Cui, Yuan Zhong, Yaqing Wang, Fenglong Ma
Abstract
Pretraining has proven to be a powerful technique in natural language processing (NLP), exhibiting remarkable success in various NLP downstream tasks. However, in the medical domain, existing pretrained models on electronic health records (EHR) fail to capture the hierarchical nature of EHR data, limiting their generalization capability across diverse downstream tasks using a single pretrained model. To tackle this challenge, this paper introduces a novel, general, and unified pretraining framework called MEDHMP 1 , specifically designed for hierarchically multimodal EHR data. The effectiveness of the proposed MEDHMP is demonstrated through experimental results on eight downstream tasks spanning three levels. Comparisons against eighteen baselines further highlight the efficacy of our approach.
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Cited by top-tier papers5
- OctoMed: Data Recipes for State-of-the-Art Multimodal Medical ReasoningTimothy Ossowski, Sheng Zhang, Qianchu Liu, Guanghui Qin et al.CVPR 2026 · 10 citations
- FEDKIM: Adaptive Federated Knowledge Injection into Medical Foundation ModelsXiaochen Wang, Jiaqi Wang, Houping Xiao, Jinghui Chen et al.EMNLP 2024 · 6 citations
- Synthesizing Multimodal Electronic Health Records via Predictive Diffusion ModelsYuan Zhong, Xiaochen Wang, Jiaqi Wang, Xiaokun Zhang et al.KDD 2024 · 4 citations
- CARER - ClinicAl Reasoning-Enhanced Representation for Temporal Health Risk PredictionTuan Nguyen, Thanh Trung Huynh, Minh Hieu Phan, Quoc Viet Hung Nguyen et al.EMNLP 2024 · 1 citation
- Unity in Diversity: Collaborative Pre-training Across Multimodal Medical SourcesXiaochen Wang, Junyu Luo, Jiaqi Wang, Yuan Zhong et al.ACL 2024
Builds on6
- A Simple Framework for Contrastive Learning of Visual RepresentationsTing Chen, Simon Kornblith, Mohammad Norouzi, Geoffrey E. HintonICML 2020 · 24,064 citations
- HiTANet: Hierarchical Time-Aware Attention Networks for Risk Prediction on Electronic Health RecordsJunyu Luo, Muchao Ye, Cao Xiao, Fenglong MaKDD 2020 · 187 citations
- AdaCare: Explainable Clinical Health Status Representation Learning via Scale-Adaptive Feature Extraction and RecalibrationLiantao Ma, Junyi Gao, Yasha Wang, Chaohe Zhang et al.AAAI 2020 · 156 citations
- Why do We Need Large Batchsizes in Contrastive Learning? A Gradient-Bias PerspectiveChangyou Chen, Jianyi Zhang, Yi Xu, Liqun Chen et al.NeurIPS 2022 · 61 citations
- UNITE: Uncertainty-based Health Risk Prediction Leveraging Multi-sourced DataChacha Chen, Junjie Liang, Fenglong Ma, Lucas Glass et al.WWW 2021 · 29 citations
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