MedCoT: Medical Chain of Thought via Hierarchical Expert
Jiaxiang Liu, Yuan Wang, Jiawei Du, Joey Zhou, Zuozhu Liu
Abstract
Artificial intelligence has advanced in Medical Visual Question Answering (Med-VQA), but prevalent research tends to focus on the accuracy of the answers, often overlooking the reasoning paths and interpretability, which are crucial in clinical settings. Besides, current Med-VQA algorithms, typically reliant on singular models, lack the robustness needed for real-world medical diagnostics which usually require collaborative expert evaluation. To address these shortcomings, this paper presents MedCoT, a novel hierarchical expert verification reasoning chain method designed to enhance interpretability and accuracy in biomedical imaging inquiries. MedCoT is predicated on two principles: The necessity for explicit reasoning paths in Med-VQA and the requirement for multi-expert review to formulate accurate conclusions. The methodology involves an Initial Specialist proposing diagnostic rationales, followed by a Follow-up Specialist who validates these rationales, and finally, a consensus is reached through a vote among a sparse Mixture of Experts within the locally deployed Diagnostic Specialist, which then provides the definitive diagnosis. Experimental evaluations on four standard Med-VQA datasets demonstrate that MedCoT surpasses existing state-of-the-art approaches, providing significant improvements in performance and interpretability. Code is released at https: //github.com/JXLiu-AI/MedCoT .
Ask about this paper
Your agent reads all of it.
Lune indexed this paper to the last equation, along with the top-tier papers that cite it. Ask a question and the answer quotes them.
Your agent calls
Luneget_paper_fulltext
Free to start. No credit card required.
Terminal
Install the CLIlune papers fulltext 678efb3b-accd-46b4-8e0b-52cac78d58cfCited by top-tier papers16
- 4KAgent: Agentic Any Image to 4K Super-ResolutionYushen Zuo, Qi Zheng, Mingyang Wu, Xinrui Jiang et al.NeurIPS 2025 · 51 citations
- Towards Faithful Reasoning in Remote Sensing: A Perceptually-Grounded GeoSpatial Chain-of-Thought for Vision-Language ModelsJiaqi Liu, Lang Sun, Ronghao Fu, Bo YangICLR 2026 · 22 citations
- Chiron-o1: Igniting Multimodal Large Language Models towards Generalizable Medical Reasoning via Mentor-Intern Collaborative SearchHaoran Sun, Yankai Jiang, Wenjie Lou, Yujie Zhang et al.NeurIPS 2025 · 16 citations
- AOR: Anatomical Ontology-Guided Reasoning for Medical Large Multimodal Model in Chest X-Ray InterpretationQingqiu Li, Zihang Cui, Seongsu Bae, Jilan Xu et al.NeurIPS 2025 · 10 citations
- KPL: Training-Free Medical Knowledge Mining of Vision-Language ModelsJiaxiang Liu, Tianxiang Hu, Jiawei Du, Ruiyuan Zhang et al.AAAI 2025 · 9 citations
Builds on8
- Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question AnsweringPan Lu, Swaroop Mishra, Tanglin Xia, Liang Qiu et al.NeurIPS 2022 · 2,727 citations
- GShard: Scaling Giant Models with Conditional Computation and Automatic ShardingDmitry Lepikhin, HyoukJoong Lee, Yuanzhong Xu, Dehao Chen et al.ICLR 2021 · 1,954 citations
- Chameleon: Plug-and-Play Compositional Reasoning with Large Language ModelsPan Lu, Baolin Peng, Hao Cheng, Michel Galley et al.NeurIPS 2023 · 515 citations
- DDCoT: Duty-Distinct Chain-of-Thought Prompting for Multimodal Reasoning in Language ModelsGe Zheng, Bin Yang, Jiajin Tang, Hong-Yu Zhou et al.NeurIPS 2023 · 252 citations
- Medical Visual Question Answering via Conditional ReasoningLi-Ming Zhan, Bo Liu, Lu Fan, Jiaxin Chen et al.ACM MM 2020 · 157 citations
Related papers
- M3CoTBench: Benchmark Chain-of-Thought of MLLMs in Medical Image UnderstandingJuntao Jiang, Jiangning Zhang, Yali Bi, Jinsheng Bai et al.ICLR 2026 · 3 citations
- ORCA: Orchestrated Reasoning with Collaborative Agents for Document Visual Question AnsweringAymen Lassoued, Mohamed Ali Souibgui, Yousri KessentiniCVPR 2026 · 1 citation
- Causal Reasoning through Two Cognition Layers for Improving Generalization in Visual Question AnsweringTrang Nguyen, Naoaki OkazakiEMNLP 2023 · 1 citation
- CARE: Towards Clinical Accountability in Multi-Modal Medical Reasoning with an Evidence-Grounded Agentic FrameworkYuexi Du, Jinglu Wang, Shujie Liu, Nicha C. Dvornek et al.ICLR 2026 · 4 citations
- MedEyes: Learning Dynamic Visual Focus for Medical Progressive DiagnosisChunzheng Zhu, Yangfang Lin, Shen Chen, Yijun Wang et al.AAAI 2026 · 8 citations
