Towards Multi-dimensional Explanation Alignment for Medical Classification
Lijie Hu, Songning Lai, Wenshuo Chen, Hongru Xiao, Hongbin Lin, Lu Yu, Jingfeng Zhang, Di Wang
Abstract
The lack of interpretability in the field of medical image analysis has significant ethical and legal implications. Existing interpretable methods in this domain encounter several challenges, including dependency on specific models, difficulties in understanding and visualization, as well as issues related to efficiency. To address these limitations, we propose a novel framework called Med-MICN (Medical Multi-dimensional Interpretable Concept Network). Med-MICN provides interpretability alignment for various angles, including neural symbolic reasoning, concept semantics, and saliency maps, which are superior to current interpretable methods. Its advantages include high prediction accuracy, interpretability across multiple dimensions, and automation through an end-to-end concept labeling process that reduces the need for extensive human training effort when working with new datasets. To demonstrate the effectiveness and interpretability of Med-MICN, we apply it to four benchmark datasets and compare it with baselines. The results clearly demonstrate the superior performance and interpretability of our Med-MICN.
Ask about this paper
Your agent reads all of it.
Lune indexed this paper to the last equation, along with the top-tier papers that cite it. Ask a question and the answer quotes them.
Your agent calls
Luneget_paper_fulltext
Free to start. No credit card required.
Terminal
Install the CLIlune papers fulltext 4c8b51e2-eb4f-4ef0-b313-76e28e8036afCited by top-tier papers2
- Vision-Language Models Guided Graph Concept Reasoning for Interpretable Diabetic Retinopathy DiagnosisQihao Xu, Xiaoling Luo, Yuxin Lin, Chengliang Liu et al.AAAI 2026
- Adaptive Multi-prompt Contrastive Network for Few-shot Out-of-distribution DetectionXiang Fang, Arvind Easwaran, Blaise GenestICML 2025
Builds on16
- SegNeXt: Rethinking Convolutional Attention Design for Semantic SegmentationMeng-Hao Guo, Cheng-Ze Lu, Qibin Hou, Zhengning Liu et al.NeurIPS 2022 · 1,385 citations
- Concept Bottleneck ModelsPang Wei Koh, Thao Nguyen, Yew Siang Tang, Stephen Mussmann et al.ICML 2020 · 1,233 citations
- Addressing Leakage in Concept Bottleneck ModelsMarton Havasi, Sonali Parbhoo, Finale Doshi-VelezNeurIPS 2022 · 163 citations
- CheXplain: Enabling Physicians to Explore and Understand Data-Driven, AI-Enabled Medical Imaging AnalysisYao Xie, Melody Chen, David Kao, Ge Gao et al.CHI 2020 · 137 citations
- Probabilistic Concept Bottleneck ModelsEunji Kim, Dahuin Jung, Sangha Park, Siwon Kim et al.ICML 2023 · 108 citations
Related papers
- MICA: Towards Explainable Skin Lesion Diagnosis via Multi-Level Image-Concept AlignmentYequan Bie, Luyang Luo, Hao ChenAAAI 2024 · 28 citations
- Model-Guided Multi-Contrast Deep Unfolding Network for MRI Super-resolution ReconstructionGang Yang, Li Zhang, Man Zhou, Aiping Liu et al.ACM MM 2022 · 32 citations
- Towards Interpretable Clinical Diagnosis with Bayesian Network Ensembles Stacked on Entity-Aware CNNsJun Chen, Xiaoya Dai, Quan Yuan, Chao Lu et al.ACL 2020 · 40 citations
- Interactive Medical Image Analysis with Concept-based Similarity ReasoningTa Duc Huy, Sen Kim Tran, Phan Nguyen, Nguyen Hoang Tran et al.CVPR 2025
- ParseCaps: An Interpretable Parsing Capsule Network for Medical Image DiagnosisXinyu Geng, Jiaming Wang, Xiaolin Huang, Fanglin Chen et al.AAAI 2025
