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Complementary Graph Representation Learning for Functional Neuroimaging Identification

Rongyao Hu, Liang Peng, Jiangzhang Gan, Xiaoshuang Shi, Xiaofeng Zhu

2022Year
9Citations
2Top-tier citations

Abstract

The functional connectomics study on resting state functional magnetic resonance imaging (rs-fMRI) data has become a popular way for early disease diagnosis. However, previous methods did not jointly consider the global patterns, the local patterns, and the temporal information of the blood-oxygen-level-dependent (BOLD) signals, thereby restricting the model effectiveness for early disease diagnosis. In this paper, we propose a new graph convolutional network (GCN) method to capture local and global patterns for conducting dynamically functional connectivity analysis. Specifically, we first employ the sliding window method to partition the original BOLD signals into multiple segments, aiming at achieving the dynamically functional connectivity analysis, and then design a multi-view node classification and a temporal graph classification to output two kinds of representations, which capture the temporally global patterns and the temporally local patterns, respectively. We further fuse these two kinds of representation by the weighted concatenation method whose effectiveness is experimentally proved as well. Experimental results on real datasets demonstrate the effectiveness of our method, compared to comparison methods on different classification tasks.

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