Are We Overconfident in Models and Results for Semi-Supervised 3D Medical Image Segmentation?
Jun Li, ZIWEI QIN
Abstract
Semi-supervised learning has become a dominant paradigm for reducing annotation costs. However, we argue that the current progress is clouded by a twofold overconfidence problem. Algorithmically, mainstream pseudo-labeling frameworks often conflate prediction confidence with uncertainty, leading to severe confirmation bias. Strategically, since multiple benchmark datasets lack dedicated validation sets, some studies use the test set for validation as well, leading to inflated performance estimates. Subsequent methods, compelled to employ the same strategy to surpass reported SOTA, trigger an arms race of overfitting. This raises concerns that the impressive numerical gains in the community may reflect overfitting rather than genuine progress. Thus, we propose a tri-space calibrated segmentation framework founded on a principled dual-axis reliability assessment engine. It explicitly decouples confidence from uncertainty and uses this signal to detect and correct confirmation bias across feature, probability, and image spaces in a collaborative manner. Across three benchmark datasets, TCSeg consistently delivers strong performance under existing evaluation protocols. More importantly, we advocate that the community report final-checkpoint results under multiple-run protocols, thereby establishing more rigorous benchmarks with a more realistic perspective. Code will be available: github.com/DirkLiii/TCSeg.
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Builds on5
- Semi-supervised Medical Image Segmentation through Dual-task ConsistencyXiangde Luo, Jieneng Chen, Tao Song, Guotai WangAAAI 2021 · 754 citations
- Rethinking Semi-Supervised Medical Image Segmentation: A Variance-Reduction PerspectiveChenyu You, Weicheng Dai, Yifei Min, Fenglin Liu et al.NeurIPS 2023 · 147 citations
- Towards Generic Semi-Supervised Framework for Volumetric Medical Image SegmentationHaonan Wang, Xiaomeng LiNeurIPS 2023 · 75 citations
- SGTC: Semantic-Guided Triplet Co-training for Sparsely Annotated Semi-Supervised Medical Image SegmentationKe Yan, Qing Cai, Fan Zhang, Ziyan Cao et al.AAAI 2025 · 1 citation
- Bidirectional Copy-Paste for Semi-Supervised Medical Image SegmentationYunhao Bai, Duowen Chen, Qingli Li, Wei Shen et al.CVPR 2023
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