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NLSR: Neuron-Level Safety Realignment of Large Language Models Against Harmful Fine-Tuning

Xin Yi, Shunfan Zheng, Linlin Wang, Gerard de Melo, Xiaoling Wang, Liang He

2025Year
38Citations
20Top-tier citations

Abstract

The emergence of finetuning-as-a-service has revealed a new vulnerability in large language models (LLMs). A mere handful of malicious data uploaded by users can subtly manipulate the finetuning process, resulting in an alignment-broken model. Existing methods to counteract fine-tuning attacks typically require substantial computational resources. Even with parameter-efficient techniques like LoRA, gradient updates remain essential. To address these challenges, we propose Neuron-Level Safety Realignment (NLSR), a trainingfree framework that restores the safety of LLMs based on the similarity difference of safety-critical neurons before and after fine-tuning. The core of our framework is first to construct a safety reference model from an initially aligned model to amplify safety-related features in neurons. We then utilize this reference model to identify safety-critical neurons, which we prepare as patches. Finally, we selectively restore only those neurons that exhibit significant similarity differences by transplanting these prepared patches, thereby minimally altering the fine-tuned model. Extensive experiments demonstrate significant safety enhancements in fine-tuned models across multiple downstream tasks, while greatly maintaining tasklevel accuracy. Our findings suggest regions of some safetycritical neurons show noticeable differences after fine-tuning, which can be effectively corrected by transplanting neurons from the reference model without requiring additional training. The code will be available at https://github.com/xinykou/ NLSR.

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