Web3 applications, particularly decentralized finance (DeFi) protocols, have grown rapidly with over 100billionlockedinsmartcontracts,attractingsophisticatedattackscausingbillionsinlosses.Whenattackoccur,securityanalystsneedtoperformfaultlocalizationtoidentifyvulnerablefunctionsandunderstandattackvectors.Thiscriticalprocesscurrentlyrequiresanaverageof16.7analysthoursperincidentduetocomplexblockchainexecutionmodels,rapidlyevolvingprotocolinteractions,andmulti−contractattackpatternsthatexceedexistinganalyticalcapabilities.Despiteitscriticalimportance,blockchainfaultlocalizationhasreceivedlimitedattentionduetofundamentalchallengesrequiringsemanticunderstandingofeconomicmodelsandprotocol−specificlogic.Existingblockchain−specifictoolstargetonlysinglevulnerabilitytypes,whiletheonlycomprehensivesolution,DAppFL,reliesonmachinelearningmodelthatmaymisssophisticatedexploitsandlacksinterpretabilityinresults.Recentadvancesinlargelanguagemodels(LLMs)demonstrateremarkablecodecomprehensioncapabilities,butexistingapplicationsfocusonproactivevulnerabilitydetectionwithminimalexplorationofpost−incidentfaultlocalization.WepresentFaultSeeker,anLLM−empoweredframeworkforblockchaintransactionfaultlocalization.Ourtwo−stagearchitecturecombinestransaction−levelforensicsforstrategicscopingwithcoordinatedspecialistagentsforsustainedreasoning.Thisdesignprovideslong−termmemorymanagementviaorchestratoragentsandspecializedattentionallocationthroughcoordinatedworkers,enablingcomprehensiveanalysisacrosscomplexmulti−contracttransactionswithoutcontextloss.WeevaluateFault−Seekeronacompileddatasetof115real−worldmalicioustransactionswithexpert−validatedannotationsspanningdiverseattackpatternsandcomplexitylevels.ResultsdemonstratethatFaultSeekersignificantlyoutperformsexistingapproaches,includingDAppFLandleadingnativeLLMs(GPT−4o,Claude3.7Sonnet,DeepSeekR1),whilemaintainingpracticalefficiency(4.4−8.6minutes)andcost−effectiveness(1.55-$4.53 per transaction).